Year Inference on the basis of evidences and observations Reference
1953 Probioticsare common in vegetable foods [6]
1954 Probioticsare opposite of antibiotics [7]
1955 Deleterious effects of antibiotics can be prevented byprobioticstherapy [8]
1965 A substance secreted by one microorganism which stimulates the growth of another [3]
1971 Tissue extracts which stimulate microbial growth [9]
1973 Compounds that build resistance to infection in the host but do not inhibit the growth of microorganisms in vitro [10]
1974 Organisms and substances that contribute to intestinal microbial balance [11]
1989 Live microbial feed supplement which beneficially affects the host animal by improving microbial balance [12]
1992 Viable mono- or mixed culture of live microorganisms which, applied to animals or man, have a beneficial effect on the host by improving the properties of the indigenous microflora [13]
1996 Living microorganisms which, upon ingestion in certain numbers, exert health benefits beyond inherent basic nutrition [14]
1999 Microbial cell preparations or components of microbial cells that have a beneficial effect on the health and well-being of the host [15]
2001 A preparation of or a product containing viable, defined microorganisms in sufficient numbers, which alter the microflora (by implantation or colonization) in a compartment of the host and by that exert beneficial health effect in this host [16]
2002 Live microorganisms that when administered in adequate amount confer a health benefit on the host [17]
2003 Probiotics can be defined as “as live microbes which transit the gastro-intestinal tract, and benefits the health of the consumer [18]
Table 1: Probiotics outline from the instigation to the current applications.