Items Controlled asthma (n=29) Uncontrolled asthma (n=39) P-value MMP-9 (ng/ml)     <0.001 Range 550-1190 900-2000 Mean ± SD 853 ± 219 1425 ± 309 TIMP-1 (ng/ml)     <0.001 Range 320-670 450-810 Mean ± SD 480 ± 114 635 ± 88 MMP-9/TIMP-1 Ratio     <0.001 Range 1.5-2.2 1.6-2.6 Mean ± SD 1.78 ± 0.15 2.23 ± 0.28

Table 2: Serum levels of MMP-9, TIMP-1 and MMP-9/TIMP-1 ratio in patients with controlled and uncontrolled asthma. Independent samples t-test.