n Baseline K+ S6c ET-1
Fresh 5 20 ± 8 153.7 ± 53 16.3 ± 4 290 ± 31
24 h 3 77 ± 10* 228.3 ± 40 139.4 ± 40* 254.4 ± 81
KN93 5 77 ± 9* 95.8 ± 25^ 55.5 ± 8 87.8 ± 23^
XeC 4 71 ± 9* 118 ± 46 68.7 ± 7 175.3 ± 5
Values are presented as absolute values of intracellular calcium in nM. Values are presented as mean ± SEM. Inhibitor was added prior to incubation. Fresh represent non-incubated arteries. * P < 0.05 represent significant compared to fresh. ^ P < 0.05 represent significant compared to 24 h, XeC = xestospongin C.
Table 3: Absolute value of intracellular calcium [Ca2+]i induced by K+, S6c and ET-1 in rat middle cerebral arteries.