Time Group I (60) Group II (60)
Mean ± SD Mean ± SD
Baseline 60.5 ± 56.6 71.0 ± 92.3
3 months 44.0#± 40.4 42.8#± 40.8
6 months 40.2#± 40.6 40.2#± 36.2
12 months 39.4#± 40.9 38.2#± 30.4
18 months 37.9#± 38.3 33.4#± 29.5
24 months 37.9#± 38.3 33.4#± 29.5
Group Difference 0.833
Time Difference 0.091
Group by Time Interaction 0.970
# indicates significant difference with from their baseline values (P< 0.05)
Table 6: Opioid intake (morphine equivalents in mg).