Point Score
Development Cohort
No. with outcome/No. of patient (%)
Validation Cohort No. with outcome/No. of patient (%)
Model mRS < 2
Strata of Score
1 (≤ 0)
1/146 (<1)
0/108 (0)
2 (1-2)
20/152 (13)
8/114 (7)
3 (3-4)
80/162 (49)
71/190 (37)
4 (5)
58/78 (74)
82/118 (70)
Point Score
<0
0/93 (0)
0/68 (0)
0
1/53 (2)
0/40 (0)
1
8/75 (11)
5/56 (9)
2
12/77 (26)
3/58 (5)
3
27/65 (42)
16/68 (23)
4
44/97 (55)
55/122 (45)
5
58/78 (74)
82/118 (70)
ROC Area
0.859
0.847
Model mRS < 3
Strata of Score
1 (≤ 0)
2/146 (1)
2/108 (2)
2 (1-2)
44/152 (29)
23/114 (20)
3 (3-4)
111/162 (69)
138/190 (73)
4 (5)
71/78 (91)
106/118 (90)
Point Score
<0
0/93 (0)
0/68 (0)
0
2/53 (4)
2/40 (5)
1
14/75 (19)
6/56 (11)
2
30/77 (39)
17/58 (11)
3
36/65 (55)
43/68 (63)
4
75/97 (77)
95/122 (78)
5
71/78 (91)
106/118 (90)
ROC Area
0.886
0.884
Model mRS > 4
Strata of Score
1 (≤ 1)
10/170 (6)
6/208 (3)
2 (2-3)
13/113 (12)
8/90 (9)
3 (4-6)
43/129 (33)
27/113 (24)
4 (≥ 7)
96/126 (76)
80/119 (67)
Point Score
0
3/141 (2)
3/120 (2)
1
7/29 (24)
3/88 (3)
2
3/49 (6)
2/49 (4)
3
10/64 (15)
6/41 (14)
4
12/39 (30)
12/48 (25)
5
17/57 (30)
10/46 (22)
6
14/33 (42)
5/19 (26)
7
17/32 (53)
17/28 (59)
8
13/20 (65)
12/26 (46)
9
16/21 (76)
7/14 (50)
10
17/18 (94)
12/18 (67)
11
16/18 (89)
9/9 (100)
≥12
17/17 (100)
23/23 (100)
ROC Area
0.866
0.876
Table 2:
Validation of the prognostic index: comparing the model performance by strata of the point score and the point score.
