Table 1

	Warfarin	Dabigatran	Rivaroxaban
Target	Factors II, VII, IX, X	Factor X	Factor Xa
Dose	Adjusted per INR	150mg BID	10mg Daily
Monitoring	INR	N/A	N/A
Renal Adjustment?	N/A	Yes	Yes
Prodrug	No	Yes	No
Antidote	Vitamin K	Not available	Not available
Bridging required	Yes	No	No
FDA labeled indications	VTE treatment and prophylaxis Thrombosis prevention in AF Prosthetic heart valves Secondary yocardial infarction prophylaxis	Thrombosis prevention in AF	VTE prophylaxis in the setting of hip and knee replacements.

Table 1: Currently available oral anticoagulants, their doses and reversal.