Antioxidant Antioxidant Location Type of action Proteins Ferritin cytoplasm chelation Fe2+ Transferrin extra cellular fluid chelation Fe2+ Lactoferrin extra cellular fluid chelation Fe2+ Ceruloplasmin extra cellular fluid chelation Cu2+, oxidation Fe2+, scavenger O2- Albumin extra cellular fluid chelation Cu2+, scavenger OH◦, LOO◦, HOCl Compounds with small molecular mass Vitamin E membranes scavenger OH◦, LOO◦, HOCl Ubiquinone membranes scavenger OH◦, LOO◦, HOCl Carotenes membranes scavenger OH◦, LOO◦, HOCl, 1O2 Vitamin C cytoplasm scavenger OH◦, O2- Reduced glutation cytoplasm, mitochondria scavenger OH◦, O2- Uric acid blood prevents lipid peroxidation Bilirubin blood prevents lipid peroxidation

Table 2: Main antioxidant compounds, location and mechanism.