Figure 1: Schematic illustration showing receptor specific dimerization of somatostatin receptor subtypes in absence or presence of agonist. SSTR1 exist as monomer with or without agonist. SSTR2 exist as a constitutive dimer and dissociates upon agonist treatment. SSTR3 is a preformed dimer and following treatment with agonist dissociates partially to monomer. SSTR4 exist as dimer and dimerization is further stabilized in presence of agonist treatment. Conversely, SSTR5 in basal condition exist as monomer however, upon agonist treatment exhibited dimerization.