Figure 2: Histograms depicting relative FRET efficiency in HEK-293 cells stably transfected with SSTR subtype 1-5. FRET efficiency was determined at cell surface by using microscopic Pb-FRET analysis in control and upon SST treatment. Changes in relative FRET efficiency are indicative of receptor dimerization. Note the distinct but significant changes in SSTR2 and SSTR5 upon agonist treatment.