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Figure 3: Schematic illustration showing heterodimerization of somatostatin receptor subtypes and consequent modulation of downstream signaling pathways. Signaling pathways indicated represent only those which have been identified so far upon receptor heterodimerization. Pathways indicated in red and green identify inhibitory and stimulatory role of SSTR subtypes respectively. This illustration was constructed using the online pathway builder from Protein Lounge (http://www.proteinlounge.com). |