| F8 gene abnormality |
Inhibitor-positive |
Inhibitor-negative |
Total
(n=24) |
p |
Odds ratio |
IC 95% |
| Total of inversions |
4 |
10 |
14 |
1 |
0.93 |
0.11-8.50 |
| Intron 22 inversion |
4 |
9 |
13 |
1 |
1.18 |
0.14-10.64 |
| Intron 1 inversion |
0 |
1 |
1 |
|
Undefined |
|
| Point mutations |
2 |
5 |
7 |
1 |
0.96 |
0.06-8.9 |
| Missense |
0 |
3 |
3 |
|
Undefined |
|
| Polymorphism |
1 |
0 |
1 |
|
Undefined |
|
| Missense+Polymorphism |
1 |
3 |
4 |
1 |
0.77 |
0.06-9.07 |
| Splice site |
0 |
1 |
1 |
|
Undefined |
|
| Nonsense |
1 |
1 |
2 |
0.50 |
2.66 |
0.02-222.13 |
| Splice site + nonsense |
1 |
2 |
3 |
1 |
1.25 |
0.01-28.27 |
| Unknown mutations |
2 |
2 |
4 |
0.55 |
0.33 |
0.02-6.03 |
n: number of patient, p: significance, IC: confidence interval |
