CYP2C9
CYP2C19
CYP2D6
CYP3A4/5
Other CYP-route
Amlodipine
+
Betaxolol
+
+
Bisoprolol
+
+
Candesartan
+
+
Captopril
+
Carvedilol
+
+
+
+
+
Chlorothiazide
+
Diltiazem
+
+
+
+
Doxazosin
+
+
+
Enalapril
+
Eplerenone
+
Felodipine
+
Guanabenz
+
Hydrochlorothiazide
+
Indapamide
+
Irbesartan
+
+
+
Isradipine
+
Losartan
+
+
+
+
Nebivolol
+
Nicardipine
+
+
+
+
Nifedipine
+
+
Nimodipine
+
Nisoldipine
+
Olmesartan
+
Propranolol
+
+
+
+
+
Quinapril
+
Ramipril
+
Timolol
+
+
Torsemide
+
+
Triamterene
+
+
+
Valsartan
+
+
Verapamil
+
+
+
+
Table 1:
Antihypertensive drugs substrates of CYP2C9, CYP2C19, CYP2D6, CYP3A4/5 [35].
