Alleles Primers sequence (5’- 3’) Probe sequence CYP2C9*2 ctgcggaattttgggatg 5’- r6g - cattgaggaccgtgttcaag -bhq-3’   taaggtcagtgatatggagtaggg 5’- fam - cattgaggactgtgttcaagag -bhq-3’ CYP2C9*3 caaatgccctacacagatgc 5’- r6g - ccagagataccttgaccttctc -bhq-3’   gatactattaatttggggacttcg 5’- fam - ccagagatacattgaccttctc -bhq-3’ VKORC 1173 acctgggctatcctctgttc 5’- fam - cctagtccaagagtcgatgatc -bhq-3’   gggaggatagggtcagtg 5’- r6g - ctagtccaagggtcgatgatc -bhq-3’ VKORC1 1542 tcagccccactccatacaatc 5’- r6g - ctcatcacggagcgtcctg -bhq-3’   ccagttagttacctccccacatc 5’- fam- ctcatcaccgagcgtcctg -bhq-3’ СYP4F2 tgcctcatcagtgttttcgg 5’- r6g - caacccagctgtgtggcc -bhq-3’   ttgagggaggtgatgttggatac 5’- fam - caacccagctatgtggccg -bhq-3’ GGCX tatgtctttcgccgcaggt 5’- r6g - tgttggcaagcttggtaact-bhq-3’   gaagaatggcaggaaaagatac 5’- fam - tgttggcaaccttggtaact-bhq-3’ CYP2D6*3 tggcaatgtcctacgcttc 5’- fam - tgagcacaggatgacct -bhq-3’   ctctcaccttctccatctctgc 5’- r6g - tgagcacggatgacct -bhq-3’ CYP2D6*4 ggcaagaagtcgctggaccag 5’- r6g- cccccaggacgcccct-bhq-3’   ttgctcacggctttgtccagg 5’- fam- cccccaagacgcccctt-bhq-3’ CYP1A2*1F attctgtgatgctcaaagggtg 5’- fam - ctgtgggcacaggacgca -bhq-3’   aaggagggactaggctgagg 5’- r6g - ctgtgggcccaggacgc -bhq-3’

Table 4: Primers and probes using for genotyping by real-time PCR.