Product INN Name Biomarker Scope Ziagen abacavir HLA-B*5701 Safety Herceptil trastuzumab HER2 receptor Efficacy Glivec imatinib c-kit Efficacy Trisenox Arsenic trioxide PML/RARa Efficacy Erbitux cetuximab EGFR/K-Ras Efficacy Tarceva erlotinib EGFR Efficacy Sprycel dasatinib PH+Chromosome Efficacy Celsentri maraviroc CCR5 coreceptor Efficacy Tasigna milotinib PH+Chromosome Efficacy Vectibix panitumumab K-Ras Efficacy Tyverb lapatinib HER2 Efficacy Iressa gefitinib EGFR Efficacy Multiple tradenames carbamazepine HLA-B*1502 HLA-A*3101 Safety Multiple tradenames Phenytoin HLA-B*1502 Safety Multiple tradenames Tamoxifen CYP2D6 Efficacy- Interactions Multiple tradenames Clopidogrel CYP2C19 Efficacy Abilify aripiprazole CYP2D6 Safety Xeloda capecitabine DPD Safety Onsenal# celecoxib# CYP2C9 Safety Faslodex fulvestrant Estrogen receptor Efficacy Viracept nelfinavir CYP2C19 Safety Fasteurtec rasburicase G6PD Safety

Table 1: Products authorised in Europe that carry genomic marker information in the label (product information) relevant to prescribing. A list of products linked to certain genomic markers in Europe including the area the marker concerns as an indicator of areas covered and includes all sections of SPC ( product label). This list is not exhaustive but indicative and where relevant information as a guide to the usage of the product is included in the label.