Figure 1: Influence of atorvastatin, simvastatin and ezetimibe on NOS3 mRNA expression in HUVEC. Values are shown as mean and SEM and were compared with the vehicle control stimulated with TNFα [(0 tnf); dotted line) by one-way ANOVA followed by Tukey post-test. HUVEC were treated for 24 h and stimulated with human TNFα (10 ng/mL) 6 h before RNA extraction. Data were obtained from 4-6 independent experiments and mRNA expression was calculated using the comparative Ct method using the HMBS as endogenous reference.