Likely Phenotype |
Genotypes |
Examples of Diplotypes |
Ultrarapid metabolizer: normal or increased activity (~5–30% of patients) |
An individual carrying two increased-activity alleles (*17), or one functional allele (*1) plus one increased-activity allele (*17) |
*1/*17, *17/*17 |
Extensive metabolizer: homozygous wild-type or normal activity (~35–50% of patients) |
An individual carrying two functional (*1) alleles |
*1/*1 |
Intermediate metabolizer:heterozygote or intermediate activity (~18–45% of patients) |
An individual carrying one functional allele (*1) plus one loss-of-function allele (*2–*8) |
*1/*2, *1/*3 |