Figure 3: Copy Number Variation analysis of DME genes. Results are shown for all 30 samples and 4 Coriell gDNA controls in CopyCaller Software. Sample 4 carries 4 copies of CYP2D6 as detected by the CYP2D6 intron 2 assays (blue arrow). The CYP2D6 exon 9 assay (red arrow) detects 3 full-length CYP2D6 alleles. The fourth copy is a CYP2D6*36 allele with an exon 9 gene conversion to CYP2D7 sequences.