| [Ethnic groups |
Region Of Russian Federation |
n |
Polymorphic marker |
Population characteristics |
Genotypes n (%) |
Allelic variants |
Ref. |
| EM |
IM |
PM |
UP |
*1 |
*2 |
*3 |
*17 |
| Russians |
Tomsk |
130 |
*2 |
Allergic diseases |
81 (66,9) |
38(31,4) |
2 (1,7) |
n.d. |
0,83 |
0,17 |
n.d. |
n.d. |
[28] |
| Tomsk |
62 |
*2,*3 |
lymphoproliferative disorders |
n.d.1 |
n.d. |
n.d. |
n.d. |
0,86 |
0,14 |
0,0 |
n.d. |
[37] |
| Moscow and the Moscow Region |
395 |
*2 |
Ischemic heart disease |
288 (72,7) |
101(25,5) |
7 (1,8) |
n.d. |
0,85 |
0,15 |
n.d. |
n.d. |
[36] |
| Moscow and the Moscow Region |
40 |
*2,*3,*17 |
Ischemic heart disease |
20 (50,0) |
12 (30,0) |
0 (0,0) |
8 (20,0) |
0,71 |
0,15 |
0,0 |
0,14 |
[35] |
| 146 |
*2 |
Healthy |
111 (76,1) |
31 (21,2) |
4 (2,7) |
n.d. |
0,83 |
0,13 |
n.d. |
n.d. |
| Tomsk |
82 |
*2 |
Healthy |
64 (78,0) |
16 (19,5) |
0 (0,0) |
n.d. |
0,88 |
0,12 |
n.d. |
n.d. |
[34]2 |
| 87 |
*3 |
Healthy |
87 (100,0) |
0 (0,0) |
0 (0,0) |
n.d. |
1 |
n.d. |
0,0 |
n.d. |
| Astrakhan |
52 |
*2 |
Healthy |
40(77,0) |
8 (16,0) |
4(7,0) |
n.d. |
0,85 |
0,15 |
n.d. |
n.d. |
[30] |
| Voronezh |
290 |
*2,*3 |
Healthy |
228 (78,7) |
56 (19,3) |
6 (2,0) |
n.d. |
0,86 |
0,11 |
0,03 |
n.d. |
[38] |
| Tatars |
Kazan |
97 |
*2 |
Ischemic heart disease |
76 (78,4) |
20 (20,6) |
1 (1,0) |
n.d. |
0,86 |
0,14 |
n.d. |
n.d. |
[39] |
| The Republic of Tatarstan |
130 |
*2,*3 |
Acid-related
disorders |
56 (43,1) |
62 (47,7) |
12 (9,2) |
n.d. |
0,67 |
0,12 |
0,21 |
n.d. |
[40] |
| Astrakhan |
50 |
*2 |
Healthy |
40 (80,0) |
7 (14,0) |
3 (6,0) |
n.d. |
0,87 |
0,13 |
n.d. |
n.d. |
[30] |
| Kalmyks |
Astrakhan |
50 |
*2 |
Healthy |
31 (62,0) |
13 (26,0) |
6 (12,0) |
n.d. |
0,85 |
0,15 |
n.d. |
n.d. |
[30] |
| Tuvinians |
The Republic of Tuva |
88 |
*2 |
Healthy |
63 (71,7) |
24 (27,2) |
1 (1,1) |
n.d. |
0,85 |
0,15 |
n.d. |
n.d. |
[34] |
| 88 |
*3 |
Healthy |
84 (95,4) |
4 (4,6) |
0 (0,0) |
n.d. |
0,98 |
n.d. |
0,02 |
n.d. |
| Buryats |
The Republic of Buryatia |
88 |
*2 |
Healthy |
54 (61,3) |
31 (35,2) |
3 (3,5) |
n.d. |
0,79 |
0,21 |
n.d. |
n.d. |
[34] |
| 88 |
*3 |
Healthy |
77 (87,5) |
10 (11,4) |
1 (1,1) |
n.d. |
0,93 |
n.d. |
0,07 |
n.d. |
| Yakuts |
The Sakha Republic (Yakutia) |
88 |
*2 |
Healthy |
54 (61,3) |
27 (30,6) |
7 (7,9) |
n.d. |
0,77 |
0,23 |
n.d. |
n.d. |
[34] |
| 87 |
*3 |
Healthy |
79 (90,8) |
8 (9,2) |
0 (0,0) |
n.d. |
0,95 |
n.d. |
0,05 |
n.d. |
| Altayans |
Altai Republic |
87 |
*2 |
Healthy |
64 (73,5) |
20 (23,0) |
3 (3,5) |
n.d. |
0,85 |
0,15 |
n.d. |
n.d. |
[34] |
| 87 |
*3 |
Healthy |
80 (92,0) |
7 (8,0) |
0 (0,0) |
n.d. |
0,96 |
n.d. |
0,04 |
n.d. |
| Chechens |
Astrakhan |
50 |
*2 |
Healthy |
41(82,0) |
7 (14,0) |
2 (6,0) |
n.d. |
0,87 |
0,13 |
n.d. |
n.d. |
[30] |
| Carachays |
The Republic of Karachay-Cherkessia |
125 |
*2 |
Healthy |
92 (73,6) |
31 (24,8) |
2 (1,6) |
n.d. |
0,86 |
0,14 |
n.d. |
n.d. |
[31] |
| Circassians |
77 |
*2 |
Healthy |
53 (68,8) |
19 (24,7) |
5 (6,5) |
n.d. |
0,81 |
0,19 |
n.d. |
n.d. |
[31] |
| Ingushes |
Astrakhan |
50 |
*2 |
Healthy |
44 (88,0) |
4 (8,0) |
2 (4,0) |
n.d. |
0,92 |
0,08 |
n.d. |
n.d. |
[30] |
Dagestans
(Laks, Dargins, Avars) |
Makhachkala |
30 |
*2 |
Healthy |
26 (86,7) |
4 (13,3) |
n.d. |
n.d. |
0,93 |
0,07 |
n.d. |
n.d. |
[32] |
1n.d. = Not determined for the study population by authors.
2In the study by Makeeva et al. [34] prevalence of CYP2C19*2 and CYP2C19*3 was studied in separate groups |
