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Figure 2: Urinary Organic Acids from Patients with Methylmalonic Aciduria. Diagnostic Peaks are: 3, methylcitric acid [6.89 ± 0.06]; 9, methylmalonic acid [8.60 ± 0.06]; 12, 3-hydroxyproponic acid [9.98 ± 0.21]. A) Untreated Methylmalonicaciduria patients showed highly elevated MMA, methylcitric acid and 3-hydroxypropionic acid. B) Diet controlled MMA patient; An abnormal peak corresponding to hippuric acid can be seen, along with a smaller peak of methylmalonic acid (Ghoraba et al. [34]) |