Fold Change in RSV BAL Compared to Control AOE Day 1 Day 3 Day 5 Day 9 Day 25 1-Cys peroxiredoxin protein −1.0 −6.1 — −4.1 — Catalase — −2.5 −2.1 — — Cu/Zn SOD 1 −2.3 −3.4 −2.0 −2.0 — Glutathione peroxidase 1 −1.8 −2.3 — 1.3 — Glutathione S-transferase — — — −6.0 — Glutathione S-transferase omega 1 −6.8 −3.6 −2.3 −2.0 1.3 Glutathione S-transferase, alpha 4 −2.2 — — — — Glutathione S-transferase, mu 1 — −4.0 −7.0 −1.7 1.4 Glutathione S-transferase, mu 2 — −4.3 — 3.4 −1.3 Glutathione-disulfide reductase — — — 3 — Nonselenium glutathione peroxidase −2.6 — −4.2 −1.3 1.2 Peroxiredoxin 6 — −3.1 −3.9 −4.1 1.3 Peroxiredoxin 2 2.7 2.4 −2.1 1.7 — Thioredoxin 1 — 1.5 — — 1.1

Table 2: Differential expression of antioxidant proteins in bronchoalveolar lavage of respiratory syncytial virus-infected mice. Shown are high probability antioxidant protein identifications and their expression (in terms of fold changes in RSV BAL compared to control mice) at different days of p.i. from peptide mass fingerprinting in MALDI-TOF/MS. BAL, bronchoalveolar lavage; —, not determined. Reprinted with permission of the American Thoracic Society.Copyright © 2014 American Thoracic Society [8,11].