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Figure 1: Schematic flow from genetic code to drug response. The study of the inherent genetic code is termed “genomics”. The genome can be modified by environmental factors and study of these factors is termed “epigenomics”. Translation of the genome can be modified by RNA factors and study of the interplay and output of these factors is called “transcriptomics”. Characterization of the subsequent protein output is called “proteomics”. “Metabolomics” is the study of the small molecules that are the product of the above biologic functions. Ultimately these biologic interactions result in the phenotypic trait observed as drug response. |