Variablesa Partial regression coefficient SE R2 after entry p-value
Age -0.00546 0.002 0.0564 0.011
D1 0.0671 0.029 0.4844 0.024
D2 -0.0478 0.048 0.5288 0.325
D3 0.156 0.041 0.5922 0.000
LN_INR4 -0.323 0.053 0.6757 0.000
CYP2C9 -0.146 0.032 0.7015 0.000
VKAA -0.147 0.041 0.7053 0.000
VKGA -0.333 0.065 0.7503 0.000
Admixture
Index
2 -0.0593 0.052 0.7629 0.257
3 -0.111 0.055 0.047
4 -0.108 0.049 0.031
Amiodarone -0.132 0.108 0.7659 0.223
Constant value of the model equation is 1.565 (SE: 0.196).
a Variables are listed in the order they were incorporated into the model using stepwise regression analysis.
Table 5: Summary of attributes for equation 2 of the pharmacogenetic warfarin Md prediction in Puerto Ricans using the derivation cohort from the VACHS.