Gene AberationType Aberation Prognosis Ethnicity BTNL2 SNP rs2076530 predisposition German, Portugese, Danish and Caucasians (low level risk) No effect African American and Japanese   SNP rs2076530+rs9268480 Predisposition European Americans and African Americans NOD Deletion 6 Base Deletion Nod2 Predisposition   NOTCH Polymorphism Polymprphism to Notch4 Predisposition   Anxa11 SNP rs1049550 Predisposition German and African Americans SNP rs1049550*T Protective

Table 1: Genetic aberrations of HLA associated genes and prognosis of ethnic groups harboring them.