| 
      
        |   | Males  | Females | Overall | p ▪  |  
        | Age (mean±SD) | 68.17±10.7 | 67.41±13 | 68±11 | 0.44 |  
        | Smoking | 95% | 16% | 80.6% | <0.001 |  
        | Packs/year | 61.3±29.1 | 36.18±18.9 | 60.52±29 | <0.001 |  
        | Histology |   |   |   |   |  
        | Adenocarcinoma | 24% | 50.3% | 27.9% | <0.001 |  
        | Squamous cell | 45.4% | 11.6% | 40.5% |   |  
        | Small cell | 23% | 23.1% | 22.9% |   |  
        | Others ▪ | 7.6% | 15.4% | 8.7% |   |  
        | Stage |   |   |   |   |  
        | I,II | 20.5% | 18.9% | 20.4% | 0.009 |  
        | IIIA,IIIB | 46.2% | 35% | 44.5% |   |  
        | IV | 33.3% | 46.2% | 31.1% |   |  | 
  
    | ? SD: standard deviation ? p: statistical significance for the comparison between the two sexes
 ? Others: adenosquamous, large cell, undifferentiated, carcinoid
 | 
  
    | Table 1: Overall and sex-related epidemiological and clinical characteristics of the
patients. |