Overall, similar macrophage activities were observed around BAG and -TCP granules. However, temporarily increased foreign body giant cell (FBGCs) accumulation was observed after implantation of hASC seeded -TCP granules as compared to BAG granules at week 4. G1 G4 = groups 1 - 4; arrows with asterisks indicates statistical differences between BAG and -TCP.
Figure 6: Overview on semi-quantitative scoring of macrophage and foreign body giant cell activity around biomaterial granules.