Groups
(number)
CFU-F
(per 106 МNC)
Primary cultivation (days) MSC yield
(per 1 CFU-F)
Donors (n=12) 34 (26-51) 14 (12-17) 1400
Lymphoma (n=28)
NHL (n=12)
LH (n=16)
16 (5-43)*
14 (4-29)**
18 (7-46)0,06
26 (17-34)**
29 (20-35)**
23 (11-30)
970 (606-3630)
884 (545-1600)
970 (688-2380)
ММ (n=6) 41 (7-63) 26 (21-34)* 9180 (1099-16920)
AL (n=7) 39 (7-45) 19 (18-20)*0,06 742 (377-1105)
АА (n=21) 43 (8-60) 18 (13-24)* 695 (422-1940)
Note: Data are presented as median and interquartile range. * - p <0.05, ** - p <0.01 - significance of differences between patients and donors by U - Mann-Whitney test.
Table 1: CFU-F number and the efficiency of MSC expansion.