Figure 5: Schematic representation of this study. (A) Preparation of conditioned medium (CM). (B) adipose-derived mesenchymal stem cells (ADSCs) or genemanipulated ADSCs were cultured in murine insulinoma cell line-derived CM (MIN6-CM) for 3 weeks and then divided into two groups. (C) Morphological change of ADSCs and subclones cultured with MIN6 conditioned medium. (D) ADSC with PANC-CM. (E) Polymerase chain reaction (PCR) analysis of Ins2.