Authors Experimental model Administration route Effect of cell types on the regenerative potential Reference number
Iwase et al. Hindlimb ischemia,
Rat
Intramuscular Autologous,
BM-MSC>BM-MNC
10
Lu et al. Limb ischemia,
Clinical
Intramuscular Autologous,
BM-MSC>BM-MNC
13
Mazo et al. Chronic MI,
Rat
Intramyocardial Allogeneic,
BM-MSC>BM-MNC
11
Mathieu et al. Chronic MI,
Canine
Intramyocardial Autologous,
BM-MSC < BM-MNC
12
MSCs: Mesenchymal Stem Cells; MNCs: Mononuclear Cells; MI: Myocardial Infarction; BM: Bone Marrow
Table 1: Comparative functional studies between MSCs and MNCs for regenerative therapy in various experimental settings.