Figure 4: Transcripts of genes expressed in human cardiovascular progenitors were elevated at day 30 when compared with day 7 in the HO-1 MSC+ hESC-CM group. Gene expression changes shown were identified using real time PCR in the group of animals transplanted with human embryonic stem cell-derived cardiomyocytes plus hemeoxygenase 1 overexpressing mesenchymal stem cells. Fold changes were calculated relative to gene expression in the animals receiving cardiomyocytes alone at the corresponding timepoint in vivo. Data are shown +/- standard errors. Asterisks indicate statistical significance at p < 0.05.