Figure 3: (A) Insertion sites distribution was analyzed in four distance categories inside genes. The hystogram confirms the classical profile of the lentiviral vector to integrate inside genes, rather than in the close proximity of the TSS. (B) Frequency of the vector insertions on chromosomes was analyzed by GTSG- QuickMap software. Integration distribution of the LV-CMV-eGFP-miR669a2x vector is represented in green (target set) and 1.000.000 random insertions (reference set) detected in mouse genome (Random Set Mus Musculus ENS52) are shown in red.