Figure 3: Response as a hyperbolic function of receptor occupancy. Doseresponse curves for a full (A) and partial (B) agonist showing proportionality relations between the conformer binding constants (agonist, Kijx ; antagonist, Krsx), and the amplification component, Kijx as a function of the maximum stimulatory response, eB. The signal amplification factor is, here, assumed common for both full and partial agonist responses.