Efficacy eB/eA EC50 measurements Ferguson-Robertson Waud log10 Krsˆ
  Log10 BK Log10 Krsˆ Log10Kij′(τ + 1) Langmuir Slope Log10 BK Log10Krsˆ Log10Kij′(τ + 1) Langmuir * Slope  
0A2 7.24 7.00 6.86 1.14±0.05(3) 7.58 7.34 7.20 0.92±0.04(4) 6.950.03
0.51 * 7.27 6.97 6.98 1.03±0.06(4) - - - - -
0.52 7.37 7.05 7.09 1.00±0.08(4) 7.29 6.97 7.00 1.005±0.05(3) 6.82±0.07
0.54 * 7.19 6.86 6.92 0.85±0.02(4) - - - - -
0.56 7.71 7.35 7.46 0.86±0.10(4) 7.25 6.89 7.00 1.00±0.08(4) 7.05±0.07
0.565 7.A1 7.05 7.16 0.990.07(4) 7.48 7.12 7.23 0.91±0.06(6) 6.71±0.04
0.58 7.A1 7.03 7.17 1.04±0.04(4) 7.70 7.32 7.46 0.75±0.00(3) 6.84±0.04
0.77 7.86 7.22 7.74 1.68±0.02(3) 7.70 7.06 7.59 1.30±0.10(3) -
Means ± SEM
0.558 ± 0.035    7.432 ± 0.083     7.066 ± 0.054   7.17 ± 0.10(8)                                7.500 ± 0.080    7.117 ± 0.074      7.247 ± 0.098(6)
0.546 ± 0.011ˆ  7.393 ± 0.072     7.060 ± 0.061   7.130 ± 0.077(6)                            7.430 ± 0.10      7.075 ± 0.094      7.17 ± 0.11(4) 0.93 ± 0.07(4)          6.855 ± 0.071(4)
° EC50 data only available
* Slope of Langmuir relation for R (A/B).
Comparative means for the efficacies of the Ferguson-Robertson results are 1) 0.569+0.047 (6) 2) 0.556+0.012(4).
ˆ Omitting extreme points on efficacy
Table 2: Apparent binding Constants ( BK/ ), Efficacies (eB/eA), Antagonist (Krsˆ) and Agonist (Kij'(τ + 1)) Binding Components of Prenalterol at 30.0°C on the Guniea pig Cardiac β1 –Adrenoceptor.