Observed Parameter
Black and Leff
Conformer Representation
+
K
⁄
B
or K
B
/
K
B
(τ + 1)
K
ijx
τ + K
B
*
K
B
/
(1–e
B
/e
A
)
K
B
K
rsx
K
B
/
(e
B
/e
A
)
K
B
τ
K
ijx
(τ + 1)
* when τ = τ
A
= τ
B
* where K
B
= K
rsx
+ K
ijx
Table 3:
Comparison of Parameters for a Partial Agonist using the Black and Leff and Conformer-Receptor Binding Models when a Common Amplifying Process is Assumed Applicable to Full (A) and Partial (B) Agonist Responses.
