Histological evaluation of the tissue response
point value 0 1 2 3 4
average score 0 – 0.49 0.5 – 1.49 1.5 – 2.49 2.5 – 3.49 from 3.5
inflammation none mild moderate severe  
fibrosis none narrow band moderate band wide band extensive band
macrophages none mild moderate severe  
foreign body giant cells none mild moderate severe  
fibrin none little fibrin moderate amount large amount  
Table 2: The evaluation score used to estimate the tissue response of each sample including the interpretation of the average score.