Figure 3: Representative scanning electron microscopic images of endothelial cells cultured on various ligand-bound substrates for 2 hours (upper) and 48 hours (lower). Cells adhere, spread, and proliferate well on FN- (left) and VEGF-bound (center) substrates but neither cell spreading nor proliferation was observed on anti- VEGFR-2 receptor antibody–bound substrates (right). Scales are 100 micrometers