| Group |
Scaffold |
Osteoinductive agent |
Anti-resorptive agent |
Mice |
Exclusions |
| 1 |
Porous PLGA |
rhBMP-2 (10µg) |
None |
N=8 |
2 |
| 2 |
Porous PLGA |
rhBMP-2 (10µg) |
PS-1145 (low 40µg) |
N=8 |
1 |
| 3 |
Porous PLGA |
rhBMP-2 (10µg) |
PS-1145 (high 80µg) |
N=8 |
3 |
| 4 |
Porous PLGA |
rhBMP-2 (10µg) |
PS-1145 (systemic 50mg/kg) |
N=8 |
1 |
|
