6 mice MS/BS MAR BFR BV/TV AP/BS AP_L1/BS AP_only/BS TRAP/BS TRAP_only/BS 8wk Femur 1.4 1.6 1.7 1.6 1.3 2.4 1.3 2.4 2.5 16wk Femur 1.3 1.3 1.4 1.6 1.5 1.7 1.5 2.5 2.6 8wk Vertebra 1.4 1.5 1.4 1.5 1.4 2.1 1.2 2.3 2.1 16wk Vertebra 1.7 1.5 1.8 1.7 1.3 1.4 1.3 1.6 1.7 8 mice MS/BS MAR BFR BV/TV AP/BS AP_L1/BS AP_only/BS TRAP/BS TRAP_only/BS 8wk Femur 1.3 1.5 1.6 1.5 1.3 2.1 1.2 2.1 2.2 16wk Femur 1.2 1.3 1.3 1.5 1.4 1.6 1.4 2.2 2.2 8wk Vertebra 1.3 1.3 1.4 1.4 1.3 1.8 1.2 2.0 1.9 16wk Vertebra 1.6 1.4 1.6 1.6 1.3 1.2 1.2 1.5 1.5 10 mice MS/BS MAR BFR BV/TV AP/BS AP_L1/BS AP_only/BS TRAP/BS TRAP_only/BS 8wk Femur 1.3 1.4 1.5 1.4 1.2 1.9 1.2 1.9 2.0 16wk Femur 1.2 1.2 1.3 1.4 1.4 1.5 1.4 2.0 2.0 8wk Vertebra 1.3 1.3 1.3 1.4 1.3 1.7 1.2 1.8 1.8 16wk Vertebra 1.5 1.3 1.5 1.5 1.2 1.2 1.2 1.4 1.5 12 mice MS/BS MAR BFR BV/TV AP/BS AP_L1/BS AP_only/BS TRAP/BS TRAP_only/BS 8wk Femur 1.2 1.4 1.4 1.4 1.2 1.8 1.2 1.8 1.9 16wk Femur 1.2 1.2 1.2 1.4 1.3 1.4 1.3 1.9 1.9 8wk Vertebra 1.3 1.3 1.3 1.3 1.2 1.6 1.2 1.7 1.7 16wk Vertebra 1.4 1.3 1.5 1.4 1.2 1.2 1.2 1.4 1.4

Table 5: Sensitivity of the fluoresence-based histomorphometry calculated from the power analysis. Fold difference between a test and control group that can be detected based on 6, 8 10 or 12 animals per group and a confidence level of 90%.