| Variable |
Advagraf group |
Prograf group |
p-value |
| (n=30) |
(n=30) |
| Donor |
|
|
|
| age (years) |
58 ± 12 |
55 ± 12 |
ns |
| gender (male /female) n (%) |
19/11 (63.3/37.7) 4/26 (13.3/86.7) |
18/12 (60/40) |
ns |
| donor type (living/decesed) n (%) |
|
10/20 (33.3/66.7) |
ns |
| Recipient |
|
|
|
| age (years) |
53 ± 11 |
47 ± 13 |
ns |
| gender (male /female) (n) |
17/13 (56.7/43.3) |
20/10 (66.7/33.3) |
ns |
| Second transplant |
2 (6.7) |
2 (6.7) |
ns |
| Peak PRA (%) |
2.8 ± 3.1 |
2.6 ± 3.3 |
ns |
| Pre Tx diabetes, n (%) |
3 (10) |
3 (10) |
ns |
| Acute rejection, n (%) |
1(3.3) |
1(3.3) |
ns |
| Graft loss, n (%) |
0 |
0 |
ns |
| Creatinine levels (mg/dl) |
|
|
|
| day 7 |
4.1 ± 0.2 |
3.9 ± 0.2 |
<0.001 |
| day 15 |
3.1 ± 0.2 |
2.5 ± 0.1 |
<0.001 |
| day 30 |
1.9 ± 0.2 |
1.8 ± 0.2 |
ns |
| day 60 |
1.6 ± 0.2 |
1.7 ± 0.2 |
ns |
| day 90 |
1.6 ± 0.2 |
1.6 ± 0.2 |
ns |
| day 180 |
1.5 ± 0.2 |
1.4 ± 0.2 |
ns |
| Lipid levels: |
|
|
|
| Total cholesterol (mg/dl) |
|
|
|
| day 30 |
216.8 ± 28.1 |
245.0 ± 30.2 |
<0.001 |
| day 60 |
211.2 ± 23.7 |
239.3 ± 34.1 |
<0.001 |
| day 90 |
209.7 ± 19.7 |
237.8 ± 34.2 |
<0.001 |
| Triglycerides (mg/dl) |
|
|
|
| day 30 |
190.8 ± 45.8 |
226.0 ± 42.3 |
<0.001 |
| day 60 |
180.6 ± 41.0 |
214.1 ± 46.8 |
<0.001 |
| day 90 |
188.2 ± 40.6 |
222.1 ± 40.6 |
<0.001 |
| HDL Cholesterol (mg/dl) |
|
|
|
| day 30 |
88.6 ± 3.9 |
66.9 ± 14.1 |
<0.001 |
| day 60 |
88.9 ± 3.9 |
69.8 ± 14.9 |
0.001 |
| day 90 |
89.5 ± 3.6 |
66.2 ± 15.2 |
<0.001 |
|
