Factor Relative hazards 95% confidence interval p-value Acute GVHD II–IV RIC vs. MAC 0.23 0.10–0.51 < 0.001 Year of HSCT 1.27 1.07–1.52 0.01 Mixed chimerism 0.9 0.40–2.00 0.8 Relapse RIC vs. MAC 1.62 0.61–4.31 0.34 CsA + MTX 0.35 0.15–0.81 0.014 ATG 4.48 1.36–14.8 0.014 Acute GVHD I–IV 0.45 0.21–0.99 < 0.05 Mortality RIC vs. MAC 1.39 0.69–2.81 0.36 Adverse cytogenetics 2.31 1.14–4.68 0.02 ATG 2.64 1.00–7.06 0.05 Bone marrow 2.33 1.04–2.39 0.04 Transplant failure (opposite of leukemia-free survival) RIC vs. MAC 1.61 0.85–3.06 0.14 ATG 3.95 1.51–10.3 0.005 Adverse cytogenetics 2.13 1.10–4.12 0.025 Abbreviations: RIC = Reduced Intensity Conditioning; MAC = Myeloablative Conditioning; ATG = Antithymocyte Globulin; CsA = Cyclosporine; MTX = Methotrexate; GVHD = Graft-Versus-Host Disease.

Table 2: Multivariate analysis for acute GVHD of grades II–IV, relapse, mortality,and transplant failure (leukemia-free survival).