Variables Control Diseased calves P Value
TNF-α (pg/mL) 12.90 ± 0.76 13.04 ± 0.31 0.8763
IL-1β (pg/mL) 13.43 ± 0.34 18.85 ± 0.48 0.0004
IL-6 (pg/mL) 17.77 ± 0.41 26.19 ± 0.95 0.0030
IF-γ (pg/mL) 9.27 ± 0.18 12.81 ± 0.25 < 0.0001
CRP (mg/L) 29.67 ± 0.06 517.80 ± 0.12 < 0.0001
Fibrinogen (mg/dL) 411.7 ± 22.42 502.5 ± 4.11 < 0.0001
Hp (g/L) 0.11 ± 0.01 2.44 ± 0.21 < 0.0001
TNF-a Tumour necrosis factor alpha; IL-1 Interleukin 1 beta; IL-6 Interleukin 6; IF-? Interferon gamma; CRP C reactive protein; Hp Haptoglobin
Table 2: Mean values SEM of selected pro-inflammatory markers and acute phase proteins in 10 clinically healthy calves and 20 calves with acute ruminal drinking.