PM Parameters Control 101 ( cfu) 103 ( cfu) 105 ( cfu) 107 ( cfu) 109 ( cfu) RBC (1012/L) 9.26 ± 0.047a 8.89 ± 0.047b 8.67 ± 0.047c 8.47 ± 0.047c 8.25 ± 0.047d 8.05 ± 0.047e Hemoglobin(g/L) 155.61 ± 0.243a 147.66 ± 0.243b 143.76 ± 0.243c 139.84 ± 0.243d 137.02 ± 0.243e 134.82 ± 0.243f PCV (L/L) 0.46 ± 0.005a 0.414 ± 0.005b 0.392 ± 0.005c 0.368 ± 0.005d 0.318 ± 0.005e 0.306 ± 0.005e WBC (×109/L) 7.72 ± 0.042a 5.2 ± 0.042b 4.92 ± 0.042c 4.2 ± 0.042d 3.92 ± 0.042e 3.1 ± 0.042f BNeutrophil(×109/L) 0.15 ± 0.007f 0.19 ± 0.007e 0.22 ± 0.007d 0.32 ± 0.007c 0.42 ± 0.007b 0.52 ± 0.007a SNeutrophil(×109/L) 19 ± 0.462f 37.4 ± 0.462e 44.3 ± 0.462d 56.5 ± 0.462c 62.6 ± 0.462b 71.04 ± 0.462a Lympho(×109/L) 5.58 ± 0.0097a 4.92 ± 0.0097b 4.51 ± 0.0097c 3.52 ± 0.0097d 2.92 ± 0.0097e 2.62 ± 0.0097f Monocytes (×109/L) 0.52 ± 0.0069a 0.53 ± 0.0069a 0.48 ± 0.0069b 0.43 ± 0.0069c 0.33 ± 0.0069d 0.27 ± 0.0069e Eosinophils(×109/L) 0.320 ± 0.0061f 0.362 ± 0.0061e 0.408 ± 0.0061d 0.490 ± 0.0061c 0.532 ± 0.0061b 0.67 ± 0.0061a Plasma Protein (g/L) 62.66 ± 0.475e 68.90 ± 0.475d 70.20 ± 0.475d 74.70 ± 0.475c 79.64 ± 0.475b 87.20 ± 0.475a PT (seconds) 26.46 ± 0.361f 37.72 ± 0.361e 43.50 ± 0.361d 49.66 ± 0.361c 56.56 ± 0.361b 63.34 ± 0.361a APTT (seconds) 53.30 ± 0.516f 63.12 ± 0.516e 69.30 ± 0.516d 77.96 ± 0.516c 84.12 ± 0.516b 97.34 ± 0.516a Thrombo(×109/L) 407.54 ± 1.12f 549.10 ± 1.12e 634.72 ± 1.12d 707.56 ± 1.12c 779.34 ± 1.12b 837.80 ± 1.12a

Values with different superscript in a row are significantly different (P<0.05); PM: Pasteurella multocida type B: 2; PCV: Packed Cell Volume; WBC: White Blood Cells; BNeutrophils: Band Neutrophils; SNeutrophils: Segmented neutrophils; Lympho: Lymphocytes; PT: Prothrombin Time; APTT: Activated Partial Thromboplastin Time; Thrombo: Thrombocytes; cfu: Colony Forming Unit.

Table 3: Modifications in hematological parameters in mice following oral inoculation of graded doses of Pasteurella multocida type B: 2 after 120 hours of inoculation.