Vaccine
(rabbit numbers)

Papilloma sites

Protected sites

Protection rate

CRPVE1/161-169
(N=8)

24

32

24/32
(75%) a

CRPVE1/303-311
(N=5)

20

20

20/20
(100%) a

CRPVE1/245-253
(N=4)

4

12

12/16
(75%) a

CRPVE1/42-50
(N=4)

4

12

12/16
(75%) a

CRPVE1/149-157
(N=3)

0

12

12/12
(100%) b

HPV16E7/82-90
(N=4)

14

2

2/16
(12.5%)

aP=0.02 and bP=0.01 vs. HPV16E7/82-90 group, Fisher’s exact test
Table 1: Protective immunity induced by full-dose (24 shots) epitope DNA vaccination in outbred HLA-A2.1 transgenic rabbits.