Treatment groups

Challenge dose (LD50)

Survival/total

*DV20

4´102

5/10

DV10

4´102

6/10

DV5

4´102

5/10

**LV20

4´102

7/10

LV10

4´102

6/10

LV5

4´102

5/10

Alum alone

4´102

0/10
*: DV stands for dry vaccine and the numbers following DV represent
concentration of 20, 10 and 5μg of F1 antigen in a final volume of 100μl,
respectively.
**: LV stands for liquid vaccine, and the numbers following LV represent
concentration of 20, 10 and 5μg of F1 antigen in a final volume of 100μl,
respectively.
Table 1: Protection of mice against challenge with Y. pestis.