Figure 6: Survival of rLIC1343525-190 immunized hamsters after challenge with virulent leptospires. Ten hamsters were immunized with rLIC1343525-190, saline (PBS), or commercial vaccine and then challenged with L. interrogans serovar Copenhageni str. Fiocruz L1-130. None of the hamsters immunized with rLIC1343525-190 or saline survived while commercial vaccine had effective protection.