Groups IL-4 (pg/ml) IFN-γ (pg/ml)
PBS 56.1 ± 4.8 60.6 ± 0.8
C501 (pYAP97R1N) i.m. 161.2 ± 6.8 147.0 ± 11.6
C501 (pYAP97R1N) orally 172.4 ± 0.5 94.1 ± 8.3
168 strain i.m. 119.9 ± 2.4 126.1 ± 2.0
168 strain orally 67.8 ± 4.1 123.5 ± 5.0
Splenocytes were isolated 42 days after primary immunization and stimulated with purified P97R1N proteins for 72 h to determine IFN- γ and IL-4 production in the culture supernatants by ELISA.
Table 2: Cytokine induction by 3 P97R1N proteins in the splenocyte culture.