Group Tx-vac-flu (n=18) Tx-no vac-flu (n=6) Healthy-flu (n=12) Tx-vac-no flu (n=13) Fever (n [%]) 14 [78%] 6 [100%] 11 [92%] N/A Cough (n [%]) 18 [100%] 4 [67%] 12 [100%] Headache (n [%]) 5 [28%] 3 [50%] 5 [42%] Rhinorrhea (n [%]) 10 [56%] 4 [67%] 7 [58%] Sore throat (n [%]) 7 [39%] 4 [67%] 3 [25%] Malaise (n [%]) 10 [56%] 6 [100%] 8 [67%] Shortness of breath (n [%]) 10 [56%] 2 [33%] 5 [42%] Other symptoms (n [%]) 13 [72%]* 4 [67%]† 4 [33%]# Symptoms of URI in contacts (n [%]) 7 [39%] 3 [50%] 2 [17%]** ††Infiltrate on CXR (n [%]) 7 [39%] 0 [0%] 0 [0%] Tx-vac-flu=Transplant recipients who developed influenza despite influenza vaccination Tx-no vac-flu=Transplant recipients who developed influenza in the absence of influenza vaccination Healthy-flu=Healthy people who developed influenza Tx-vac-no flu=Transplant recipients who received influenza vaccination and did not develop influenza N/A=not applicable. URI=upper respiratory tract infection. CXR=Chest Plain Radiography. *Other symptoms in the tx-vac-flu group were diarrhea (4), wheezing (2), rash (1), chills (1), chest pain (1), anorexia (1), hoarseness (1), ear ache (1), and dysuria (1). †Other symptoms in the tx-no vac-flu group were anorexia (1), nausea (1), vomiting (1), and diarrhea (1). #other symptoms in the healthy-flu group were anorexia (1), wheezing (1), ear ache (1), and sweats (1). **Data available from 3 patients. ††All patients in the tx-vac-flu group, 5 patients in the tx-no vac-flu group, and 5 patients in the healthy-flu group had CXR done P=not significant for all comparisons to the tx-vac-flu group in this table.

Table 2: Clinical characteristics.