| Virus |
Virus titer at 33°С, log10 EID50/ml |
RCT1 |
Phenotype |
| 33/37°C |
33/38°C |
33/39°C |
33/40°C |
33/25°C |
| L17-MDV (Н2N2) |
9.2 |
5.0 |
6.0 |
7.0 |
7.5 |
2.5 |
ts, ca |
| NIBRG–23 (H5N1) |
6.2 |
0 |
0 |
4,7 |
6.2 |
4.0 |
non–ts, non–ca |
| 1VN/PR/CDC-RG (H5N1) |
7.7 |
1.0 |
1.0 |
7.7 |
7.7 |
4.0 |
non-ts, non-ca |
| t/T/H5N2 LAIV |
8.7 |
4.5 |
5.7 |
8.7 |
8.7 |
1.5 |
ts, ca |
| VN/H5N2 LAIV |
9.2 |
5.0 |
7.0 |
9.2 |
9.2 |
1.5 |
ts, ca |
| VN/H5N1-RG LAIV |
8.7 |
4.2 |
6.2 |
8.7 |
8.7 |
1.5 |
ts, ca |
1Reproductive capacity of influenza viruses at different temperatures - (ts and ca phenotype) was assessed by titration in eggs at the permissive (33°С), elevated (38, 39,
40°С) and low (25°С) temperatures of incubation and expressed as RCT25,38, 39 or 40= log10 EID50/ml at 33°С –log10 EID50/ml at 25, 38, 39 or 40°С. Eggs were incubated for 2
days at 33, 38, 39 and 40°C and for 6 days at 25°C. |
