Factors   Anti-HBs after 1st booster dose X2 P
No. examined < 10 mIU/ml > 10 mIU/ml
  No. % No. %
Age (years)           - 0.303Δ
10- 9 1 11.1 8 88.9
12- 17 1 5.9 16 94.1
14- 6 1 16.7 5 83.3
16-17 13 4 30.8 9 69.2
Mean ± SD   14.1 ± 2.6 13.5 ± 2.2 t=1.1 P=0.280
Gender           - 0.103Δ
Male 26 6 23.1 20 76.9
Female 19 1 5.3 18 94.7
BMI           1.147 0.766
Underweight 2 0 0.0 2 100.0
Normal R 32 5 15.6 27 84.4
Overweight 8 1 12.5 7 87.5
Obese 3 1 33.3 2 66.7
Mean ± SD   24.4 ± 5.9 19.8 ± 3.3 t = 3.283 P=0.001*
Duration ofDM              
<2 10 2 20.0 8 80.0 0.400 0.940
2- 11 2 18.2 9 81.8
4- 15 2 13.3 13 86.7
7-12 9 1 11.1 8 88.9
Mean ± SD   3.1 ± 4.5 4.5 ± 3.3 t=-1.015 P=0.316
Insulin dose              
< 30 8 1 12.5 7 87.5 - 0.936 Δ
30- 14 2 14.3 12 85.7
40+ 28 4 17.4 19 82.6
Mean ± SD   50.7 ± 23.5 40.9 ± 15.9 t=1.4 P=0.173
HBA1c           - 0.118 Δ
Less than 7 20 5 25.0 15 75.0
More than 7 25 2 8.0 23 92.0
Complications ofDM           0.773 0.379
No 42 6 14.3 36 85.7
yes 3 1 33.3 2 66.7
Hospitalization           8.198 0.017*
No 18 1 5.6 17 94.4
Once 14 1 7.1 13 92.9
Frequent 12 5 41.7 7 58.3
Anti-HBc           0.809 0.368
Negative 41 7 17.1 34 82.9
Positive 4 0 0.0 4 100.0
Anti-HCV           0.188 0.664
Negative 44 7 15.9 37 84.1
Positive 1 0 0.0 1 100.0
Table 5: Factors affecting the immune response to 1st boosting among diabetics. *P<0.05 (significant), Δ: P value based on Mont Carlo exact probability, DM: Diabetes Mellitus.