Subject Age (years) Sex Time of the first dose(days) Anti-HBs Anti-HBc Amino acid substitutions PTA26 4 M 7 + - Q129H PTA142 2 M 0 + - T126I, M133L,T143S PTA148 5 M 21 - + T126I, M133L,T143S PTA198 3 M 4 + - Wild

Table 3: Serology and amino acid substitution in completely vaccinated children with occult HBV infection. HBsAg: Hepatitis B surface antigen; HBV: Hepatitis B virus; Anti-HBs: Antibody to HBsAg; Anti-HBc: Antibody to the hepatitis B core antigen.