Figure 4: Cytokine transcript levels from mice infected and treated; infected only mice (C+); infected mice treated with fluconazole (InMed); infected mice treated with LevRad (InRad); infected mice treated with LevRad associated with fluconazole (InRadMed). The same experiments were repeated twice with similar results. Data was reported as mean+standard deviations of relative expression of iNOS enzyme and cytokine in relation to β-actin from the lungs of 5 animals per group. IFN- γ (A) ** significant (p<0.05) difference related to C+; *** significant (p<0.05) difference for InMed and InRadMed; &&& significant (p<0.05) difference related to C+ and InMed; ### significant (p<0.05) difference of InRadMed in relation with C+ and InMed. IL-10 (B) ### and ***significant (p<0.05) difference in relation to C+. iNOS (C) &&& significant (p<0.001) difference in relation to C+, InMed and InRadMed; *** significant (p<0.001) difference from the first (60 days) to the second (120 days) data reading; ### significant (p<0.05) difference in relation to C+ and InMed. TNF-alpha (D) *** significant (p<0.05) difference to C+, InMed, and InRadMed; ### significant (p<0.05) different in C+ in relation to InMed, InRad and InRadMed. IL-4 (E) *** significant (p<0.05) difference between InMed and InRad; ** significant (p<0.05) difference between InRadMed and C+ (p<0.05). TGF-beta (F) *** e ### significant (p<0.05) difference between InMed, InRad and InRadMed.